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姓 名 苏柱泉
职 称 副主任医师
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医疗特长

研究方向:呼吸介入与慢性气道疾病

研究工作:特殊光成像在慢性气道疾病中的应用研究


从医历程
科研情况

代表性科研项目:

(1)肺泡巨噬细胞功能活性在早期慢阻肺戒烟前后肺泡及小气道结构改变的作用机制研究,国家自然科学基金青年项目,主持

(2)光学成像对慢性气道疾病诊断标准的建立及智能化体系的应用,“广东特支计划”卫生健康领域榜单项目,主持

(3)基于OCT成像技术M3受体阻断对支气管哮喘平滑肌介导气道炎症和重塑的作用机理研究,广州市科技计划项目,主持

(4)噻托溴铵对早期慢阻肺小气道及肺泡结构重塑的疗效及作用机理研究,广东省教育厅项目,主持

(5)尼古丁通过α7nAchR/Notch通路介导肺泡巨噬细胞极化在慢阻肺气道重塑中的机制研究,呼吸疾病国家重点实验室自主项目,主持

(6)经呼吸道多模式诊疗机器人的临床验证与评价体系构建-国家重点研发计划“合成生物学”重点专项项目子课题,参与


代表性学术论文(第一或通讯作者):

1. Su ZQ, Guan WJ, Li SY, Feng JX, Zhou ZQ, Chen Y, Zhong ML, Zhong NS. Evaluation of the Normal Airway Morphology Using Optical Coherence Tomography. Chest. 2019 Nov;156(5):915-925.

2. Su ZQ, Zhou ZQ, Guan WJ, Fan MY, Rao WY, Chen Y, Chen XB, Zhong CH, Tang CL, Li SY, Zhong NS. Airway remodeling and bronchodilator responses in asthma assessed by endobronchial optical coherence tomography. Allergy. 2021 Aug 26.

3. Luo YL, Cheng YQ, Zhou ZQ, Fan MY, Chen DF, Chen Y, Chen XB, Zhong CH, Tang CL, Li SY, Su ZQ. A clinical and canine experimental study in small-airway response to bronchial thermoplasty: Role of the neuronal effect. Allergol Int. 2021 Aug 13:S1323-8930(21)00087-3.

4. Mo X, Jian W, Su Z, Chen M, Peng H, Peng P, Lei C, Chen R, Zhong N, Li S. Abnormal pulmonary function in COVID-19 patients at time of hospital discharge. Eur Respir J. 2020 Jun 18;55(6):2001217.

5. Zhong CH, Fan MY, Xu H, Jin RG, Chen Y, Chen XB, Tang CL, Su ZQ, Li SY. Feasibility and Safety of Radiofrequency Ablation Guided by Bronchoscopic Transparenchymal Nodule Access in Canines. Respiration. 2021;100(11):1097-1104.

6. Chen Y, Zhou ZQ, Feng JX, Su ZQ, Zhong CH, Lu LY, Chen XB, Tang CL, Digumarthy SR, Fiorelli A, Natour E, Lococo F, Petrella F, Harris K, Nakada T, Zhong NS, Li SY. Hybrid stenting with silicone Y stents and metallic stents in the management of severe malignant airway stenosis and fistulas. Transl Lung Cancer Res. 2021 May;10(5):2218-2228.

7. Zhou ZQ, Feng JX, Chen Y, Su ZQ, Zhong CH, Chen XB, Tang CL, Huang JR, Li SY. Self-expanding covered metallic stents as a transition to silicone stent implantation in management of severe post-tuberculosis bronchial stenosis. Ther Adv Respir Dis. 2021 Jan-Dec;15:17534666211019564.

8. Su ZQ, Ye TS, Chen DF, Deng XL, Chen HJ, Li SY. The Role of Bronchoscopy in COVID-19. Respiration. 2020;99(8):697-698.

9. Zhou ZQ, Su ZQ, Sun W, Zhong ML, Chen Y, Zhong CH, Chen HJ, Li SY. Postintubation Tracheal Stenosis Evaluated by Endobronchial Optical Coherence Tomography: A Canine Model Study. Respiration. 2020;99(6):500-507.

10.Mo XN, Su ZQ, Lei CL, Chen DF, Peng H, Chen RC, Sang L, Wu HK, Li SY. Serum amyloid A is a predictor for prognosis of COVID-19. Respirology. 2020 Jul;25(7):764-765.

11. Yao Y, Su Z, Chen Y, Ye Y, Lu L, Zhong C, Chen X, Tang C, Li S. Safety and efficacy of sufentanil combined with midazolam in bronchoscopy under conscious sedation: retrospective study of 11,158 cases. J Thorac Dis. 2019 Oct;11(10):4127-4134.

12. Su Z, Cheng Y, Wu Z, Zhang P, Chen W, Zhou Z, Zhong M, Luo W, Guo W, Li S. Incidence and Predictors of Tracheobronchial Tuberculosis in Pulmonary Tuberculosis: A Multicentre, Large-Scale and Prospective Study in Southern China. Respiration. 2019;97(2):153-159.

13. Su ZQ, Guan WJ, Li SY, Ding M, Chen Y, Jiang M, Chen XB, Zhong CH, Tang CL, Zhong NS. Significances of spirometry and impulse oscillometry for detecting small airway disorders assessed with endobronchial optical coherence tomography in COPD. Int J Chron Obstruct Pulmon Dis. 2018 Oct 1;13:3031-3044.

14. Su Z, Zhong C, Li S, Chen X, Chen Y, Tang C. Needle-based confocal laser endomicroscopy in the diagnosis of peripheral pulmonary nodule: a preliminary report. J Thorac Dis. 2017 Aug;9(8):2608-2612.

15. Su Z, Li S, Zhou Z, Chen X, Gu Y, Chen Y, Zhong C, Zhong M, Zhong N. A canine model of tracheal stenosis induced by cuffed endotracheal intubation. Sci Rep. 2017 Mar 28;7:45357.

16. Zhou ZQ, Guo ZY, Zhong CH, Qiu HQ, Chen Y, Rao WY, Chen XB, Wu HK, Tang CL, Su ZQ, Li SY. Deep Learning-Based Segmentation of Airway Morphology from Endobronchial Optical Coherence Tomography. Respiration. 2023 Jan 19:1-10.

17. Zhong CH, Su ZQ, Luo WZ, Rao WY, Feng JX, Tang CL, Chen Y, Chen XB, Fan MY, Li SY. Hierarchical clock-scale hand-drawn mapping as a simple method for bronchoscopic navigation in peripheral pulmonary nodule. Respir Res. 2022 Sep 14;23(1):245. 

18. Su ZQ, Rao WY, Pan XY, Tang JX, Fan MY, Chen XB, Li SY. Multiple Lung Cavity Lesions, Thoracic Wall Abscess and Vertebral Destruction Caused by Streptococcus constellatus Infection: A Case Report. Infect Drug Resist. 2023 Aug 15;16:5329-5333.

19. Su ZQ, Zhong ML, Fan MY, Rao WY, Zhou ZQ, Chen Y, Chen XB, Tang CL, Zhong CH, Li SY. Airway morphological abnormalities of bronchiolitis assessed by endobronchial optical coherence tomography. Ther Adv Respir Dis. 2023 Jan-Dec;17:17534666231167351.

20. Ye YS, Chen DF, Liu M, Luo YL, Chen HJ, Zeng HK, Liu JW, Zhu YP, Song XY, Lin CQ, Su ZQ, Li SY. Autologous Airway Basal Cell Transplantation Alleviates Airway Epithelium Defect in Recurrent Benign Tracheal Stenosis. Stem Cells Transl Med. 2023 Oct 7:szad062.

21. Chen GJ, Chen XB, Rao WY, Pan XY, Li SY, Su ZQ. Airway necrosis and granulation tissue formation caused by Rhizopus oryzae leading to severe upper airway obstruction: a case report. Front Cell Infect Microbiol. 2024 Mar 4;14:1366472. 


获奖及个人荣誉:

(1) 苏柱泉(6/11); 广东医学科技奖, 广东省医学会, 科技进步, 省部二等奖, 2022(李时悦; 陈愉; 钟长镐; 唐纯丽; 陈小波; 苏柱泉; 罗为展; 周子青; 王凤燕; 梁振宇; 钟南山)

(2) 苏柱泉(1/1); 中青年呼吸精英, 医师报社2021

(3) 苏柱泉(1/1); 广州市医学会医学优秀论文二等奖, 广州市医学会,2021

(4) 苏柱泉(1/1); 广州市医学会优秀论文三等奖, 广州市医学会,2021

(5) 苏柱泉(1/1); The 7th Pacific Congress on Bronchology and Interventional Pulmonology, Asia-Pacific Congress on Bronchology and Interventional Pulmonology, 2017

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